International Review of Ophthalmology ›› 2023, Vol. 47 ›› Issue (4): 296-301.doi: 10.3760/ cma.j.issn.1673-5803.2023.04.002

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Application of optical coherence tomography angiography on assessment of microcirculation changes in glaucoma

Zhang Yihan,  Zhang Fengyan   

  1. Department of Ophthalmology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China
  • Received:2023-02-05 Online:2023-08-22 Published:2023-08-22
  • Contact: Zhang Fengyan, Email: zhangfengyanx@aliyun.com

Abstract: Optical coherence tomography angiography (OCTA) is a novel, non-invasive ophthalmic examination technique that provides high-resolution images of microvascular. OCTA can quantitatively analyze optic disc, retinal and choroidal blood perfusion of patients with glaucoma and assess their microvascular changes. Patients with different types of glaucoma may have decreased vessel density of the optic disc, peripapillary, macular retina, choroid and abnormal indexes related to foveal avascular zone, whose changes are related to the degree of visual field defect, the thickness of the nerve fiber layer, and the thickness of the ganglion cell complex.  (Int Rev Ophthalmol, 2023, 47: 296-301)

Key words: optical coherence tomography angiography, glaucoma, vessel density, foveal avascular zone